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Professional Research Assistant

Company: University of Colorado
Location: Aurora
Posted on: June 8, 2021

Job Description:

University of Colorado Denver l Anschutz Medical Campus

Department of Medicine, Division of Allergy and Clinical Immunology

Official Title: Professional Research Assistant

Working Title: Histocompatibility Technologist in Molecular Typing

Position 00782634- Requisition 20942

The University of Colorado Denver l Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment. We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.

The University of Colorado Denver | Anschutz Medical Campus is a comprehensive urban research university serving more than 28,000 students in metropolitan Denver and online. We award nearly 4,000 degrees each year, including more graduate and professional degrees than any other Colorado public institution. With our solid academic reputation, award-winning faculty and renowned researchers, we offer 119 highly rated degree programs through 13 schools and colleges. The University of Colorado Denver | Anschutz Medical Campus is well known for its distinctive and highly productive research programs, its world-class health facilities at the Anschutz Medical Campus and its well-established partnerships in business, industry and government. These campuses currently have over $400 million in research awards each year. In addition to the wide array of health-related programs and facilities offered at our Anschutz Medical Campus, a significant number of undergraduate and graduate degree programs are taught at our comprehensive campus in the heart of downtown Denver. Denver is one of America's most vibrant urban centers and the downtown campus, located just steps from the Denver Center for Performing Arts and the LoDo District, affords our students, faculty and staff access to a broad array of academic, professional, community, recreational and cultural outlets.

Job Summary:

Performs clinical laboratory testing to determine compatibility of transplant recipients and donors, including ABO-Rh and CMV total and chimerism DNA sendouts, HLA Class I, HLA Class II, and KIR genotyping. Adheres to standards of external regulatory bodies including ABHI, CAP, and CLIA. Understands principles of histocompatibility and immunogenetics. Prepares reagents while adhering to strict quality control guidelines; performs and documents instrument function checks and preventive maintenance. Works independently and with others; readily adapts to changes in work environment; performs multiple tasks simultaneously. Communicates effectively with others. Participates in continuing education. Demonstrates initiative in accomplishing the goals of the laboratory.

Key Responsibilities:

  • Performs Class I and Class II HLA molecular and KIR molecular typing according to written protocols. Performs ABO-Rh and CMV total and chimerism DNA Sendouts according to written protocols.

Performance Standards

  • Maintains sample identity and integrity throughout sample logging, processing, testing and reporting of results.
  • Observes all record keeping, QC, and experiment number conventions in DNA laboratory.
  • Reads all results accurately and performs data analysis.
  • Assigns DNA and/or KIR type.
  • Completes report and cover sheet.
  • Completes donor reports.
  • Understands and carries out DNA amplifications using all pre-PCR restrictions and standards.
  • Applies special handling to low-concentration DNA samples or when instructed through the laboratory management system.
  • Maintains competency in one or more of the below areas as determined by the supervisor:
  • Extraction:
  • Extracts DNA according to protocol.
  • Is aware of patient conditions that may affect yield and purity.
  • Knows how to calculate yield based upon 260/280 readings.
  • Dilutes samples to appropriate concentrations.
  • Maintains and operates EZ-1 and Maxwell per protocol.

  • Electrophoresis
  • Follows procedure.
  • Records data.
  • Maintains and operates agarose gel electrophoresis or eGene.

  • LabType
  • Follows procedure.
  • Records data.
  • Maintains and operates Luminex 3D instrument.

  • Next Generation Sequencing
  • Follows procedure.
  • Records data.
  • Maintains and operates Pippin Prep and/or bead isolation.
  • Maintains and operates GloMax
  • Maintains and operates MiSeq.

j. Completes ABO-Rh and CMV total and chimerism DNA Sendouts following SOP.

  • Actively participates in quality assurance program.

Performance Standards

  • Is familiar with the major steps of a validation and can lead a validation to completion with input from the Quality Unit.
  • Notifies and documents equipment malfunctions.
  • Monitors reagent inventory and notifies supervisor before additional reagents are needed.
  • Participates in reagent preparation and documents necessary information.
  • Reviews SOP's as revised and entire SOP manual per established frequency.
  • Participates in continuing education activities, including annual re-training in laboratory safety issues in handling bloodborne pathogens, chemicals, hazardous wastes and fire.
  • Performs annual unknown testing of a previously characterized sample for each test that is preformed in lab, including samples from external proficiency testing programs.
  • Complete annual DNA competency assessment successfully.
  • Records results accurately and concisely communicates them as needed to transplant personnel and supervisors.

Performance Standards

a. Verifies presence of appropriate paperwork including test requisition, HLA typing sheets and summary report prior to review by supervisor and/or director.

b. Double-checks all paperwork for accuracy and completeness prior to review by supervisor and/or director.

c. Completes reports and relays results in a timely fashion; notifies appropriate personnel when further testing is needed and when results will be ready.

d. Notifies Supervisor of reporting errors found and follows through with necessary documentation.

  • Work ethic: performs assays according to established protocols, follows safety guidelines, uses universal precautions and works well with others and independently.

Performance Standards

a. Follows all established policies and protocols related to testing, reagent preparation and quality control.

b. Participates in the introduction and implementation of new procedures and in the evaluation of new instruments.

c. Willing to occasionally work unscheduled hours; manages daily work schedule and time effectively.

d. Demonstrates effective and pleasant communication skills and human relations; provides quality customer service.

e. Notifies Supervisor and/or Director of assay or equipment malfunctions, which compromise test quality.

f. Performs additional tasks as requested by Supervisor and/or Director.

g. Organizes workload for maximum efficiency; assists co-workers; contributes to a positive working environment.

  • Maintains a clean and safe working environment.
  • Communication: Maintains communication with the team.

Performance Standards

  • Is engaged through electronic means (ex. Teams and email) as well as in-person discussions.
  • Reviews and follows electronic schedule
  • Uses My.Leave and University systems as required for staff.

Salary and Benefits:

The salary range (or hiring range) has been established at $35,600 to $60,000. This position is not eligible for overtime compensation.

The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training.

The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The University of Colorado offers a full benefits package. Information on University benefits programs, including eligibility, is located at Employee Services.

University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background checks for all new employees prior to their employment.

The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. Alternative formats of this ad are available upon request for persons with disabilities.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Benefits: https://www.cu.edu/employee-services/benefits.

Total Compensation Calculator: https://www.cu.edu/employee-services/total-compensation

Diversity and Equity:

Please click here for information on disability accommodations: https://www1.ucdenver.edu/offices/human-resources/employee-relations-performance/ada-compliance

Office of Equity: https://www1.ucdenver.edu/offices/equity

The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

Minimum Qualifications:

B.A. or B.S. degree in biological science from an accredited college or university.

Applicants must meet minimum qualifications at the time of hire.

Preferred Qualifications:

Certification by the American Board of Histocompatibility and Immunogenetics (ABHI) as a Certified Histocompatibility Technologist (CHT) or ABHI Certified Histocompatibility Specialist (CHS) or certification as a Medical Technologist by the American Society of Clinical Pathologists, MT(ASCP).

Keywords: University of Colorado, Aurora , Professional Research Assistant, Other , Aurora, Colorado

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